The majority of Americans experience some degree of insulin resistance, largely due to a food environment rich in processed foods, carbs, and sugars. This insulin resistance impacts female and male hormones in distinct ways.
In women, as insulin resistance increases, the body produces more insulin to regulate blood sugar. Elevated insulin levels inhibit aromatase, the enzyme responsible for converting testosterone to estrogen in the ovaries. As a result, women have higher testosterone and lower estrogen levels, which can lead to polycystic ovary syndrome (PCOS). PCOS is characterized by irregular menstrual cycles, increased facial hair, acne, male-pattern baldness, and fat accumulation around the abdomen because the ovaries are unable to convert testosterone into estrogen.
In men, elevated insulin levels cause subcutaneous fat tissue to produce more aromatase. This leads to an increased conversion of testosterone into estrogen, causing symptoms like the development of breast tissue, softer skin, and other signs of feminization.
So, how can Semaglutide and Tirzepatide help in this situation?
- Improved Insulin Response: Semaglutide and Tirzepatide retrain the body to respond appropriately to insulin, lowering both glucose and insulin levels to more normal, healthy ranges.
- Reduced Appetite and Food Intake: These medications help reduce appetite, which in turn decreases glucose and insulin levels, promoting the reversal of insulin resistance.
- Weight Loss: Significant weight loss is another benefit, and weight loss independently improves insulin sensitivity. As clients lose weight, many report feeling better, experiencing less pain, and becoming more active, which leads to increased muscle mass. Building muscle is one of the most effective ways to combat insulin resistance.
- Improved Sleep: Anecdotally, clients also report better sleep as they lose weight. Quality sleep is crucial for maintaining healthy insulin sensitivity.
Overall, Semaglutide and Tirzepatide support a comprehensive approach to improving insulin sensitivity, reversing insulin resistance, and alleviating hormone-related symptoms.