At ReGen Men’s Clinic, we take a data-driven, physiologic approach to male optimization. Among the treatments we offer are three highly specialized procedures — Bocox, Scrotox, and HoleTox — designed to support vascular function, pelvic floor health, and neuromuscular balance.
These aren’t gimmicks. They’re well-tolerated, localized therapies that address real physiologic dysfunction and help improve sexual health outcomes in men across a wide age spectrum.
Bocox: Enhancing Penile Blood Flow and Smooth Muscle Relaxation
Bocox involves the intrapenile injection of botulinum toxin type A, targeting the corpus cavernosum. While best known for its aesthetic uses, Botox also exerts a localized effect on smooth muscle tone and vasodilation.
- Mechanism: By inhibiting acetylcholine at the neuromuscular junction, Bocox promotes smooth muscle relaxation and reduces sympathetic tone, allowing improved arterial inflow and decreased resistance in erectile tissue.
- Clinical Rationale: Particularly helpful in men with mild ED, delayed response to PDE5 inhibitors, or high sympathetic drive (“fight or flight” dominance).
- Results: Improved rigidity, enhanced responsiveness to ED meds, and in some patients, increased satisfaction with erectile quality.
Scrotox: Functional & Cosmetic Benefits for the Scrotum
Scrotox is the injection of botulinum toxin into the dartos muscle of the scrotum.
- Mechanism: Reduces involuntary contractions of the scrotal musculature, leading to a more relaxed, lower-hanging appearance and improved comfort.
- Indications: Excessive sweating, tight scrotal tone, post-exercise discomfort, or purely aesthetic preference.
- Additional Benefits: Some patients report increased sensation and reduced hypersensitivity.
HoleTox: Addressing Hypertonicity in the Pelvic Floor
HoleTox is a neuromodulator injection delivered into the internal and external anal sphincter regions. It’s a treatment often overlooked in male pelvic floor dysfunction.
- Mechanism: Reduces excessive sphincter tone, which can contribute to sexual performance issues, pelvic pain, or dyssynergic defecation.
- Clinical Use Cases: Anal hypertonicity, pelvic floor dysfunction, enhancing sexual comfort.
Combining Therapies for Maximum Benefit
These treatments are often used adjunctively with:
- P-Shot (PRP for erectile tissue regeneration)
- Focused shockwave therapy (to restore vascular health)
- Hormone optimization (testosterone, DHEA, thyroid)
- Peptide therapies (BPC-157, PT-141, Kisspeptin)
Our protocol design depends on objective biomarkers, patient goals, and underlying causes of dysfunction. No two plans are the same.
Who Are These Treatments For?
We evaluate candidates based on vascular status, sexual history, pelvic muscle tone, and response to prior interventions. These procedures are safe, effective, and can be especially useful for men who:
- Have mild to moderate ED or decreased sexual stamina
- Experience high pelvic floor tone or tension-related pain
- Want non-hormonal support for confidence and function
Final Thoughts
At ReGen Men’s Clinic, we believe in treating root causes — not just symptoms. Bocox, Scrotox, and HoleTox are targeted, physiologic therapies with real clinical benefits when applied in the right context.
If you’re curious whether they’re right for you, our team is here to answer questions and create a data-backed, individualized treatment strategy.